Others

Azido-PEG2-hydrazide-Boc is a polyethylene glycol (PEG) derivative serving as a linker in the development of proteolysis targeting chimeras (PROTACs) [1].

5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) 是一种具有抗癌作用的萜类化合物。

5-O-TBDPS-1,2-di-O-isopropy lidene-3-keto-alpha-D-xylofuranoside is a Carbohydrate.

Troriluzole 是一种具有口服活性谷氨酸调节剂，具有抗癌活性。Troriluzole 可提高位于神经胶质细胞的兴奋性氨基酸转运体的表达，可用于研究脊髓小脑性共济失调、阿尔茨海默病和广泛性焦虑症 (GAD) 。

Thioridazine hydrochloride (Standard) 是一种可用于分析的标准物质，通常用作 Thioridazine hydrochloride 的研究和分析中参考的标准样品。Thioridazine hydrochloride (Mellaril) 是一种多巴胺受体D2家族蛋白的拮抗剂，有抗精神病和抗焦虑活性。它也是一种PI3K-Akt-mTOR 信号通路的抑制剂，具有抗血管生成作用。它在多种类型的癌细胞中显示出抗增殖和凋亡诱导作用，对靶向癌症干细胞具有特异性。

2-Acetamidofluorene 是一种强致癌物。2-Acetamidofluorene 可用于诱导肝细胞癌 (HCC) 和多原发肿瘤。

Isoamyl salicylate是一种酯类化合物，广泛应用于生物化学实验和药物合成研究。

5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside utilized in the synthetic process of deoxyribonucleic acid (DNA) or nucleic acid.

11-Ketodihydrotestosterone is a metabolite of 11β-Hydroxyandrostenedione. It is an active androgen and is also a potent androgen receptor (AR) agonist (Ki: 20.4 nM, EC50: 1.35 nM for human AR).

Benzyl-PEG4-Azido is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

19 alpha-Hydroxyasiatic acid shows significant anticoagulant effect on the extrinsic pathway.

2,3-Diethylpyrazine是一种吡嗪衍生物，广泛应用于生物化学实验和药物合成研究。

ADTN hydrobromide (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively). ADTN hydrobromide stimulates production of cAMP in rat striatal homogenates, a process that is reduced by 70% in the presence of the dopamine antagonist fluphenazine at a concentration of 1 μM.

4,4-Dimethyl-2-cyclopenten-1-one为Apocyniveneti Folium的源植物衍生的天然产物，展示了对多种肿瘤细胞的高选择性毒性。

Anti-Trypanosoma cruzi agent-4是克氏锥虫抑制剂。Anti-Trypanosoma cruzi agent-4 可用于感染的研究。

3,5-Dimethylcyclopentane-1,2-dione是一种含有羰基的环戊烷衍生物，广泛应用于生物化学实验和药物合成研究。

Org 43553 是口服具有活力的低分子量 (LMW) 促黄体生成素受体(LH-R)激动剂，能够激动人 LH (EC50: 3.7 nM)和 FSH 受体(EC50: 110 nM) 。Org 43553 能够用于研究内分泌。

Tezacitabine 是一种抑制细胞生长和细胞毒性的抗代谢物。 Tezacitabine 是一种核苷类似物，具有双重作用机制。 Tezacitabine 不可逆地抑制核糖核苷酸还原酶，并可在复制或修复过程中掺入 DNA，导致 DNA 链终止。 Tezacitabine 在细胞周期的 G1 期和 S 期阻断肿瘤细胞并诱导凋亡细胞死亡。 Tezacitabine 具有治疗白血病和实体瘤的潜力[1][2]。

WNK-IN-B is an inhibitor of Wnk signalling. WNK-IN-B is a cell-permeable diaminoacridine derivative that targets the CCT domain of SPAK and OSR1 via reversible binding. WNK-IN-B selectively suppress hypotonic shock-induced WNK signaling pathway activation

Fluorescein-PEG5-NHS ester, a PEG-based PROTAC linker, facilitates PROTAC synthesis[1].

ORY-1001 is a KDM1A inhibitor (IC50 <20nM) with high selectivity against related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B >100uM, SMOX 7uM). Treatment of THP-1 (MLL-AF9) cells with ORY-1001, results in a time/dose dependent me2H3K4 accumulation a

MRV03-070，作为大肠杆菌素激活肽酶ClbP的抑制剂，展现出与生物合成前体前肌动蛋白相似的作用机制，其IC50值为69 nM。

(Rac)-Tezacaftor ((Rac)-VX-661) 是Tezacaftor 的外消旋体。Tezacaftor 是一种F508delCFTR 校正子。(Rac)-Tezacaftor 可以用于囊性纤维化的研究。

Antiparasitic agent-8 (Compound 9) exhibits potent antiparasitic activity against Hymenolepis nana, while demonstrating low levels of cytotoxicity [1].

Glutathione synthesis-IN-1 (DC-1)是谷胱甘肽合成抑制剂。

H-Val-Tyr-OH 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T66956，CAS号为 3061-91-4。

Glycerol Tripropionate (三丙酸甘油酯) 是由甘油和丙酸形成的三酯，作为无色至浅黄色液体在食品/化妆品中用作乳化剂和稳定剂，在制药中作为溶剂/载体。

Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

B 581 is an inhibitor that specifically blocks farnesylated.

DNP-PEG3-DNP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Nampt-IN-8 是一种 NAMPT 抑制剂 (IC50: 0.183 μM)，也是较好的 NQO1 底物。Nampt-IN-8 能够诱导活性氧 (ROS) 产生，并促使细胞凋亡 (apoptosis) 。

SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.

TAT-DEF-Elk-1 is a cell-penetrating peptide Elk-1 inhibitor.

Cardanol triene是一种天然的酚类物质，对tyrosinase具有抑制作用(IC50=40.5 μM)，可用于生命科学领域的相关研究。

BTK inhibitor 19 is a highly selective, covalent BTK inhibitor ( IC 50 = 2.7 nM).

Milrinone Lactate is a positive inotropic cardiotonic compound. Milrinone Lactate has vasodilator properties, inhibiting cAMP phosphodiesterase type 3 activity in the myocardium and vascular smooth muscle.