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Antifection
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Antibacterial
Antibiotic
Antifection
Antifungal
Beta-lactamase
CCR
EBV
Enterovirus
GluCls
HBV
HCV Protease
HIV Protease
HSV
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Parasite
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Antifection
Antifection
感染是病原体入侵组织、繁殖以及宿主组织对感染源及其产生的毒素的反应。抗感染药物包括抗生素、抗真菌药物、抗原生动物药物和抗病毒药物。
HIT100554791
Miconazole
T0344
22916-47-8
Miconazole (R18134) 是一种具有抗菌作用的咪唑类抗真菌剂。
Antibacterial
Antibiotic
Antifection
Antifungal
NOS
Potassium Channel
HIT106687580
Methyl 4-Hydroxyphenylacetate
TN1436
14199-15-6
Methyl 4-Hydroxyphenylacetate has potent inhibitory activity against tobacco mosaic virus (TMV).
Antifection
HIT107406299
Monomethylsulochrin
TN4579
10056-14-1
Monomethylsulochrin shows antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus. It shows moderately inhibitory effects on the human bacterial pathogen Helicobacter pylori with the MIC value of 28.9+/-0.1 microM.
Antibacterial
Antibiotic
Antifection
HIT106716225
Metronidazole
T1079
443-48-1
Metronidazole (Metronidazol) 是一种合成的硝基咪唑衍生物,一种抗生素和抗原虫剂,具有口服活性和血脑屏障渗透性。Metronidazole 可用于治疗或预防厌氧菌引起的系统或局部感染。
Antibacterial
Antibiotic
Antifection
Apoptosis
Hydrogenase
NADPH
Parasite
HIT214316193
Sorokinianin
TN5039
162616-73-1
Sorokinianin is a phytotoxin, it has antifungal activity, it is highly effective in suppressing spore germination of F. solani (75%) at 100 ug/ml concentration.
Antifection
HIT212671126
BRL44385
T10615
114778-60-8
BRL44385 is an effective and selective inhibitor of the replication of HSV-1 and HSV2, Epstein-Barr virus (EBV), and varicella-zoster virus (VZV).
Antifection
HSV
HIT219228903
Ganolactone A
TN8599
173268-82-1
Ganolactone A 是一种天然产物,可用作天然产物对照品,用于生命科学相关领域的研究,其产品编号为 TN8599。
Antifection
HIT213887340
Prehelminthosporol
TN4822
1619-13-2
Prehelminthosporol is a phytotoxin, it may play an important role in pathogenesis by killing or weakening plant cells in advance of the growing hyphae and facilitating nutrient uptake and further growth of the fungus in plant tissue.
Antifection
HIT218851900
CEF14, EBV Rta Protein (28-37)
TP1507
216862-58-7
CEF14, EBV Rta Protein (28-37), is the HLA A24-restricted epitope from the Epstein-Barr virus Rta Protein (28-37).
Antifection
HIT212711734
Rubropunctatin
T26167
514-66-9
Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.
Antibacterial
Antifection
Antifungal
Others
HIT212014841
Maribavir
T2162
176161-24-3
Maribavir (GW257406X) 是一种可口服的苯并咪唑核苷化合物,具有抗巨细胞病毒的活性。
Antifection
HCV Protease
Virus Protease
HIT102920548
L-Lysine
T2A2498
56-87-1
L-Lysine (Aminutrin) 是一种人类必需氨基酸,能增加钙吸收,减少糖尿病相关疾病和改善肠道健康,可用于疱疹的研究。
Antifection
Endogenous Metabolite
HSV
Virus Protease
HIT102880213
Licoarylcoumarin
TN4433
125709-31-1
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-HIV activity, and it has inhibitory effects on xanthine oxidase.
Antifection
cAMP
HIV Protease
HIT213885382
Canthin-6-one N-oxide
TN3584
60755-87-5
Canthin-6-one N-oxide has broad spectrum antifungal, leishmanicidal and trypanocidal activities.
Antifection
Parasite
HIT100069072
Carabrone
TN1114
1748-81-8
Carabrone 是分离自Carpesium abrotanoides 果实的一种倍半萜,表现出显著抗肿瘤活性和抗菌活性,如灰霉病菌Botrytis cinerea,炭疽病菌Colletotrichum lagenarium 和禾白粉菌Erysiphe graminis。
Antibacterial
Antifection
HIT213885240
Canophyllal
TN3583
14440-40-5
Canophyllal shows antiplasmodial activity against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs.
Antifection
NO Synthase
HIT213886993
Artanin
TN3450
96917-26-9
Artanin displays promising inhibition against both MSSA and MRSA with minimal inhibitory concentrations (MICs) of 8-64 ug/ml, but very weak against Gram-negative pathogen and yeast with MICs of 256 to ≥1024 ug/ml.
Antifection
Cholinesterase (ChE)
HIT104971689
Ferruginol
TN1642
514-62-5
Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce apoptosis in non-small cell lung cancer (NSCLC) cells.
Antifection
Apoptosis
Bcl-2 Family
Caspase
HSV
PARP
HIT213884722
2-Acetoxy-3-deacetoxycaesaldekarin E
TN2747
18326-06-2
2-Acetoxy-3-deacetoxycaesaldekarin E shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro.
Antifection
HIT213886075
Isonardoperoxide
TN4314
205248-65-3
Isonardoperoxide shows strong antimalarial activity against Plasmodium falciparum malaria (6.0 × 10-7 M).
Antifection
Parasite
HIT212665402
Dehydroglaucine
TN1561
22212-26-6
Dehydroglaucine is an acetylcholinesterase inhibitor, it shows antimicrobial activity against Staphylococcus aureus, Mycobacterium smegmatis, Candida albicans, and Aspergillus niger.
Antibacterial
Antifection
HIT212522138
Calycanthoside
TN1463
483-91-0
Calycanthoside (Isofraxidin 7-O-beta-D-Glucoside) 是一种从当归中分离出来的天然化合物。 Calycanthoside 具有抗炎和抗菌作用。
Antifection
NO Synthase
HIT213884672
(2S)-7,4'-Dihydroxy-3'-prenylflavan
TN3214
376361-96-5
7,4'-Dihydroxy-3'-prenylflavan has antibacterial activity.
Antifection
HIT103501181
Longistylin C
TN4449
64125-60-6
Longistylin A and longistylin C show some cytotoxic effects, with IC(50) values of 0.7-14.7 microM against the range of cancer cell lines. Longistylin A and longistylin C, and betulinic acid show a moderately high in vitro activity against the chloroquine
Antifection
HIT213885835
Lipiferolide
TN4443
41059-80-7
Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitory activity against several tumor cells, it possesses cytotoxic activity against KB cells. Liriodenine also has antiplasmodial activity.
Antifection
Parasite
Telomerase
Transferase
HIT214316094
Oplopanone
TN4717
1911-78-0
Oplopanone exhibits noteworthy anti-plasmodial activity against Plasmodium falciparum strain.
Antifection
HIT214314568
Mucrolidin
TN1955
227471-20-7
Mucrolidin shows weak antibacterial activity.
Antibacterial
Antifection
HIT212665398
Decarine
TN1556
54354-62-0
Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages.Decarine inhibits fMLP/CB-induced elastase release with IC(50) values < or = 5.53 microg/mL.
Antifection
HIT214316113
Physalin D
TN4776
54980-22-2
Physalin D shows antimalarial activity; it also exhibits a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H(37)Rv strain of 32 microg/mL. Physalin D displays considerable cytotoxicity against several cancer cell lines. It
Antifection
TNF
HIT103281667
Haplopine
TC0017
5876-17-5
Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the cells.
Antibacterial
Antifection
Tyrosinase
HIT214315722
Chloramultilide B
TN3637
1000995-47-0
Chloramultilide B exhibits moderate in vitro antifungal activity.
Antifection
Antifungal
HIT214315858
Effusanin A
TN3920
30220-43-0
Effusanin A 是一种存在于Isodon rugosus 之中的天然产物。 它具有 DNA 损伤和抗菌作用。
Antibacterial
Antifection
Raf
HIT103275702
3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid
TN2849
477873-63-5
2-O-beta-d-Glucosyloxy-4-methoxybenzenepropanoic acid[3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid] exhibits glutathione S-transferase (GST) inhibitory and antifungal activities.
Antifection
HIT214316271
Yadanzioside I
TN5267
99132-95-3
Yadanzioside I shows strong antiviral activity.
Antifection
TMV
HIT214314594
Saikosaponin I
TN2172
103629-71-6
Saikosaponin I shows strong inhibition activity against influenza virus WSN33.
Antifection
HIT214314552
Yadanzioside L
TN2321
99132-97-5
Yadanzioside L shows strong antiviral activity.
Antifection
TMV
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