Antifection

Sanggenol A 抑制甲型流感病毒和肺炎球菌神经氨酸酶，因此可作为双重作用的抗感染试剂。

Dehydrocrebanine has strong activity against promyelocytic leukemia cells (HL-60) with an IC50 of 2.14 ug/mL. It also shows potent antimalarial activity with an IC50 value of 70 ng/ml.

Tioconazole (Vagistat) 是一种广谱性的抗真菌咪唑衍生物。它抑制几种皮肤真菌和几种酵母菌的 MIC50分别小于 3.12 mg/L 和 9 mg/L。

Methyl 6-hydroxyangolensate shows antifungal and antibacterial activities.

Horminone has antimicrobial activity, it can inhibit the protein synthesis in several types of bacteria; it can inhibit the in vitro growth of Trypanosoma cruzi, 30 microM drug concentration producing total inhibition of growth. After administration of plant extracts containing Horminone has possibility of toxic effect.

Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resulting in cytochrome c release from the mitochondria. A mixture of uncarinic acid E and 27-O-p-(

Eritoran Tetrasodium, a TLR4 receptor antagonist, is used potentially for the treatment of type 2 diabetes.

Mulberrofuran H exhibits potent antifungal activity against phytopathogenic fungi Colletotrichum orbiculare, Phytophthora capsici, Corynespora cassiicola and Fusarium oxysporum.

Fumitremorgen B is a mycotoxin, it exhibits a certain degree of genotoxicity, it can cause DNA damage in human lymphocytes; it shows an inhibitory activity on the cell cycle progression of mouse tsFT210 cells in the M phase, with the MIC value of 26.1 mic

Pendulone could be a valuable chemopreventive agent, it shows strong inhibition on the effect of the cell cycle induced by TPA and shows potent anti-tumor-promoting activity for an in vivo two-stage carcinogenesis test.

22-Dehydroclerosterol has antibacterial activity against against E. coli, S. aureus, and H. pylori.

4-O-Methylsappanol shows activity against this fungus against Beauveria bassiana.

(4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one shows growth inhibitory activity in vitro versus bloodstream forms of African trypanosomes, with the IC(50) value in the range of 1-3 microg/mL.

1,7-Dihydroxy-2,3-methylenedioxyxanthone exhibits antiulcerogenic, anti-oxidation, and antihyperalgesic activities and can inhibit carrageenan-induced hyperalgesia.

Arteannuin N is one of the main component of Arteannuin. Arteannuin has antimalarial activity. Arteannuin can degrade the level of TNF-α in rats with ostarthritis,and effectively inhibit the inflammation.

Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic ingredients, as they suppress UVB-induced MMP-1 expression.

7-Ethoxyrosmanol has cytotoxic and antimicrobial activities.

3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3 ug/mL. It has a lower capacity of stimulating murine peritoneal macrophages to release nitric oxide and tumoural-alpha necrose factor

Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186) and was modified to develop more potent anti-AIDS agents. Moronic acid is a new structural lead for anti-EBV drug development, can substantially reduce the numbers of EBV particles produced by the cells after lytic induction. Morolic and moronic acids have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1 as indicated by in vitro.

Cefepime Dihydrochloride Monohydrate (Cefepime HCl) 是一种广谱头孢菌素，对革兰氏阳性菌和革兰氏阴性菌有更高的覆盖率。

Totarol ((+)-Totarol) 对几种致病性革兰氏阳性细菌、结核分枝杆菌具有抗菌作用。

9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori, it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 microM. It may have anti-inflammatory activity, it exhibits potent inhi

Veraguensin 来源于 Magnolia sp.。 Veraguensin 抑制骨吸收并显示出高抗寄生虫活性。

(+)-Syringaresinol shows antioxidant potential, it exhibits cytoprotective activity in cultured MCF-7 cells stressed by H2O2.

Valpromide (Dipropylacetamide) 是丙戊酸的羧酰胺衍生物，用于治疗癫痫和一些情感障碍。

Isobonducellin exhibits potent cytotoxic activity in Jurkat and HepG2 cells, while moderate growth inhibition against Colon205 cells.

Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. Cryptomeridiol has low activity against A. niger, T. mentagrophytes, and C. albicans. (-)-Cryptomeridiol also exhibits a significant and concentration-dependent inhibitory effect on PAF receptor binding, with inhibitory concentration (IC)(50) values of 17.5 uM.

Sideroxylin can synergistically enhance the antimicrobial activity of the alkaloid berberine (also a constituent of H. canadensis) against Staphylococcus aureus by inhibition of the NorA multidrug resistance pump.

(2S)-2'-Methoxykurarinone 是一种分离自苦参根中的化合物，具有抗炎、解热、抗糖尿病和抗肿瘤活性。它对人髓系白血病 HL-60 细胞具有细胞毒活性。它能够下调 RANKL 信号，抑制破骨细胞形成和骨吸收。

α-Cembrenediol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124625。

Clotrimazole (FB 5097) 是咪唑衍生物，有抗真菌和抗菌活性，是 P450抑制剂。

1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Methoxyphaseollidin may show moderate cytotoxic activity against KB and L1210 cells. 1-Methoxyphaseollidin also shows inhibition of lysoPAF acetyltransferase activity.

8-Epixanthatin, a light-induced growth inhibitor, mediates the phototropic curvature in sunflower (Helianthus annuus) hypocotyls, it can induce germination of O. cumana at nano- to micromolar concentrations. 8-Epixanthatin has antiprotozoal activity.

Piperolactam C possesses anti-platelet aggregation activity in vitro. It can inhibit the growth of the fungi Cladosporium sphaerospermum and C. cladosporioides.

Colutehydroquinone 是一种从Colutea arborescens 的根皮中提取的异黄酮，具有抗真菌活性。

(+)-Nortrachelogenin 是一种从 Wikstroemia indica C.A. Meyer （百里香科）中分离出来的木脂素。 (+)-Nortrachelogenin 具有抗白血病活性。