Others

QM385 is a potent inhibitor of sepiapterin reductase (SPR)(IC50 of 1.49 nM).

SLF TFA 是 FK506 结合蛋白 (FKBP) 的合成配体，对FKBP51的亲和力为 3.1 μM，对FKBP12的IC50为 2.6 μM，可用于合成PROTAC 分子。

1,2,3-Butanetriol（1,2,3-丁三醇）是一种三元醇，可用于有机合成和生化实验。

SP-8203 is a reactive oxygen species inhibitor and superoxide dismutase stimulant.

allosteric potentiator of mGlu5

GPR40 agonist 1 is an effective new GPR40 agonist (EC50s: 17 nM and 2 nM for rGPR40 and hGPR40).

CDK7-IN-16 (compound 9) 是一种 CDK 7 的有效抑制剂 (IC50: 1-10 nM)。CDK7-IN-16 能够用于研究抗癌，特别是转录异常的癌症。

TRPV2-selective blocker 1 (compound IV2-1) 为选择性TRPV2通道阻断剂，具有6.3 μM IC50，不对TRPV1、TRPV3和TRPV4通道产生影响。该化合物能够抑制巨噬细胞中TRPV2介导的Ca2+流入，进而抑制其吞噬功能。

SARM1-IN-2 是一种有效的 SARM1 抑制剂，可用于研究代谢系统和神经系统相关疾病。

NAV-2729 是有效的Arf1/Arf6活化抑制剂。

Stepronin (TTPG) 具有祛痰活性并抑制气道分泌。

Propylene carbonate是一种常用的极性非质子溶剂，广泛应用于生物化学实验和药物合成研究。

DNA-PK-IN-2 is a highly effective inhibitor of DNA-dependent protein kinase (DNA-PK), which is a complex enzyme composed of Ku70/Ku80 heterodimer and DNA-PK catalytic subunit (DNA-PKcs). With its potential applications in cancer research, DNA-PK-IN-2 demonstrates promise as a valuable tool for studying cancer diseases [1].

SKF1 is a suppressor of the ability of FK506. SKF1 inhibits cell growth in the presence of high levels of NaCl, induces cell death in low salt conditions, interacts directly with yeast mitochodria.

C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect agai

AP5 sodium 是选择性的、有效的、口服具有活力的 GPR40 受体激动剂，对内源性配体 (AgoPAM) 表现出正向变构调节效果。AP5 sodium 在大鼠和人肌醇一磷酸 (IP1) 实验中作用于 GPR40 受体，他们的 EC50值分别为 0.49 nM 和 0.8 nM。AP5 sodium 表现出研究 II 型糖尿病的潜能。

Z-DEVD-AFC 在生命科学相关研究中具有广泛的应用。

Basroparib 是一种核糖聚合酶 (PARP)抑制剂，表现出抗肿瘤效果。

Ethacrynate Sodium, the sodium salt form of ethacrynic acid, could inhibit symport of chloride, potassium, and sodium primarily in the ascending limb of Henle, but also in the proximal and distal tubules.

Azido-PEG10-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

AST 7062601 是一种高效 Ucp1 诱导剂，在原代小鼠棕色脂肪细胞中促使内源性 Ucp1 表达。AST 7062601 可能用于研究肥胖。

t-Butyl acetate-PEG3-CH2COOH is a polyethylene glycol-derived PROteolysis TArgeting Chimera (PROTAC) linker, specifically designed for incorporation into the synthesis of PROTAC molecules.

γ-Glu-Tyr (gamma-Glutamyltyrosine) 是一种对二肽基肽酶-IV (DPP-IV) 具有竞争性抑制作用的 kokumi 肽，可用于研究糖尿病。

Boc-NH-PEG10-CH2CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker utilized for PROTAC synthesis[1].

7-Methoxyflavone 是一种分离自 Zornia brasiliensis 的化合物。它能够抑制福尔马林疼痛反应神经源期的舔爪时间 (65.6%)，有外周镇痛活性，但不影响炎症期的伤害性反映。

RET-IN-5 是 RET 的有效抑制剂 (IC50: 4.57 nM)。

RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 μM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound effectively suppresses both receptor-mediated and synaptic vesicle endocytosis, demonstrating IC50 values of 9.3 μM and 7.1 μM, respectively.

JYL-273 is a TRPV1 agonist.

N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1657，CAS号为 2382942-32-5。

GSK983, a potent broad-spectrum antiviral, blocks cell proliferation and dengue virus replication by inhibiting the pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase (DHODH).

ML368 is a selective inhibitor of CYP3A4.

Lisinopril dihydrate (Standard) 是一种可用于分析的标准物质，通常用作 Lisinopril dihydrate 的研究和分析中参考的标准样品。Lisinopril dihydrate （MK-521) 是一种血管紧张素转化酶抑制剂。Lisinopri dihydrate 能够作用于高血压，充血性心力衰竭和心脏病等。

Tos-PEG9 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

A 410099.1 amide-PEG2-amine-Boc is a functionalized IAP ligand for PROTACs, consisting of an IAP ligand and an amide-PEG3 linker with a terminal amine. It is capable of forming conjugates with target protein ligands.

TCL053是一种可电离脂质，专用于高效导入活性成分（特别是核酸）至细胞。它可与二棕榈酰磷脂酰胆碱(DPPC)、聚乙二醇二肉豆蔻酰基甘油(PEG-DMG)及胆固醇共同构成脂质纳米粒(LNP)，实现Cas9 mRNA与sgRNA向骨骼肌的有效传递。

Prifinium bromide是抗胆碱能试剂，能够改善痉挛，具有止吐效果。